Additive antifibrotic effects of pioglitazone and candesartan on experimental renal fibrosis in mice.

@article{Higashi2010AdditiveAE,
  title={Additive antifibrotic effects of pioglitazone and candesartan on experimental renal fibrosis in mice.},
  author={Keishi Higashi and Takashi Oda and Taketoshi Kushiyama and Toshitake Hyodo and Muneharu Yamada and Shigenobu Suzuki and Yutaka Sakurai and Soichiro Miura and Hiroo Kumagai},
  journal={Nephrology},
  year={2010},
  volume={15 3},
  pages={327-35}
}
AIM To examine the additive protective effects of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone (Pio) and the angiotensin II receptor blocker candesartan (Cand) in a murine model of renal fibrosis: mice with unilateral ureteral obstruction (UUO). METHODS Mice were randomly assigned into four groups that after UUO received i.p… CONTINUE READING

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