Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department.

@article{Kruif2010AdditionalVO,
  title={Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department.},
  author={Martijn D. de Kruif and Maarten Limper and Herman Gerritsen and C. Arnold Spek and Desiderius P. M. Brandjes and Hugo Ten Cate and Patrick M. M. Bossuyt and Pieter H. Reitsma and Eric van Gorp},
  journal={Critical care medicine},
  year={2010},
  volume={38 2},
  pages={457-63}
}
OBJECTIVE First, to determine whether procalcitonin (PCT) significantly adds diagnostic value in terms of sensitivity and specificity to a common set of markers of infection, including C-reactive protein (CRP), at the Emergency Department. Second, to create a simple scoring rule implementing PCT values. Third, to determine and compare associations of CRP and PCT with clinical outcomes. DESIGN The additional diagnostic value of PCT was determined using multiple logistic regression analysis. A… CONTINUE READING
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