Additional considerations are required when preparing a protocol for a systematic review with multiple interventions.

@article{Chaimani2017AdditionalCA,
  title={Additional considerations are required when preparing a protocol for a systematic review with multiple interventions.},
  author={A. Chaimani and D. Caldwell and Tianjing Li and J. Higgins and G. Salanti},
  journal={Journal of clinical epidemiology},
  year={2017},
  volume={83},
  pages={
          65-74
        }
}
OBJECTIVES The number of systematic reviews that aim to compare multiple interventions using network meta-analysis is increasing. In this study, we highlight aspects of a standard systematic review protocol that may need modification when multiple interventions are to be compared. STUDY DESIGN AND SETTING We take the protocol format suggested by Cochrane for a standard systematic review as our reference and compare the considerations for a pairwise review with those required for a valid… Expand
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