Additional bioactive Lyso-PAF congeners from the sponge Spirastrella abata.

@article{Alam2001AdditionalBL,
  title={Additional bioactive Lyso-PAF congeners from the sponge Spirastrella abata.},
  author={Naseer Alam and Bok Hee Bae and Jongki Hong and Chong Ock Lee and Boo Ahn Shin and Kwang Sik Im and Jee H Jung},
  journal={Journal of natural products},
  year={2001},
  volume={64 4},
  pages={533-5}
}
A known (1) and four new (2--5) lyso-PAF (platelet activating factor) derivatives were isolated from the sponge Spirastrella abata. Two of them are unprecedented in having a methoxy group at C-2'. The structures have been determined by combined spectroscopic methods. Their inhibitory effect on the biosynthesis of cholesterol and cytotoxicity against human solid tumor cell lines are reported. 

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