Additional Transaminations by Insoluble Particle Preparations of Rat Liver

@article{Hird1950AdditionalTB,
  title={Additional Transaminations by Insoluble Particle Preparations of Rat Liver},
  author={F. J. R. Hird and E. V. Rowsell},
  journal={Nature},
  year={1950},
  volume={166},
  pages={517-518}
}
Braunstein and Kritzmann1 suggested that transamination in pigeon breast muscle was a general reaction involving most of the amino-acids; Cohen2 was unable to confirm these results, and pointed out the lack of experimental controls. Further work by Cohen3 with purified enzyme preparations suggested that the transamination reactions were limited to L-glutamate + oxalacetate \[rlharr] α-ketoglutarate + L-aspartate and L-glutamate + pyruvate \[rlharr] α-ketoglutarate + L-alanine. Slower but… 

Infra-nuclear Distribution of Transaminases

It will be shown that the cell nucleus contains significant transaminase activities, mostly localized in the nuclear sap, resolvable by chromatography.

The oxidation of L-amino acids by mitochondria from rat liver.

Amino acid metabolism in locust tissues.

Transamination Reactions in Succharomyces frugilis

The transfer of the amino group from aspartic acid or leucine to a-ketoglutaric acid was not inhibited by any one of five antibiotics tested, but was partially inhibited by M-semicarbazide.

Aspartate AminotransferaseActivityand IsoenzymeProportionsin Human LiverTissues

The mitochondrial enzyme averaged 81 % of the total activity in normal adult human liver (n = 4) and its contribution was dramatically reduced in single specimens of human fetal liver and hepatoblastoma tissue.

THE OXIDATION OF GLUTAMATE AND ALANINE BY LIVER MITOCHONDRIA.

Transamination reactions in uredospores of Puccinia helianthi.

  • J. Smith
  • Biology
    Journal of general microbiology
  • 1963
Various transamination reactions were observed in germinating uredospores of Puccinia helianthi Schw and the presence of glutamate-aspartate transaminase enzymes in the u redospores suggests that the uredosphere could synthesize a large number of amino acids.

THE CYCLOPHORASE COMPLEX OF ENZYMES

The cyclophorase system catalyses a group of synthetic condensations which are all distinguished by the necessity for sparking by some members of the citric acid cycle, and the need for inhibition by 2:4‐dinitrophenol and gramicidin.
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The preliminary experiments with the more reliable method for glutamic acid determination showed that although most tissues are capable of bringing about transamination, the different tissues show great differences in detail.