Addition of isradipine (Lomir) results in a better renal function after kidney transplantation: a double-blind, randomized, placebo-controlled, multi-center study.

@article{Riemsdijk2000AdditionOI,
  title={Addition of isradipine (Lomir) results in a better renal function after kidney transplantation: a double-blind, randomized, placebo-controlled, multi-center study.},
  author={Iza C van Riemsdijk and P. G. Mulder and Johan W. de Fijter and Jan Anthonie Bruijn and Johannes P. van Hooff and Andries J. Hoitsma and Adam M Tegzess and Willem W Weimar},
  journal={Transplantation},
  year={2000},
  volume={70 1},
  pages={122-6}
}
BACKGROUND After successful kidney transplantation patients may suffer from the adverse effects due to the use of calcineurin inhibitors. Calcium channel blockers are effective in the treatment of hypertension and may ameliorate cyclosporine- (CsA) induced impairment of renal function after kidney transplantation. Calcium channel blockers may also modulate the immune-system which may result in reduction of acute rejection episodes. PATIENTS AND METHODS From June 1995 till 1997 the effect of… CONTINUE READING