Addition of human recombinant bone morphogenetic protein-2 to inactive commercial human demineralized freeze-dried bone allograft makes an effective composite bone inductive implant material.

@article{Schwartz1998AdditionOH,
  title={Addition of human recombinant bone morphogenetic protein-2 to inactive commercial human demineralized freeze-dried bone allograft makes an effective composite bone inductive implant material.},
  author={Zvi Schwartz and Andrea Somers and James T. Mellonig and David Carnes and John M. Wozney and David D. Dean and David Lee Cochran and Barbara D Boyan},
  journal={Journal of periodontology},
  year={1998},
  volume={69 12},
  pages={1337-45}
}
COMMERCIAL PREPARATIONS OF HUMAN DEMINERALIZED freeze-dried bone allograft (DFDBA) vary in their ability to induce new bone formation. This study tested the hypothesis that inactive DFDBA can be used as an effective carrier of recombinant human bone morphogenetic protein-2 (rhBMP-2). Two batches of active DFDBA were used as controls. Two batches of DFDBA, previously shown to be inactive, were treated with vehicle or with 5 or 20 microg rhBMP-2 and implanted into the calf muscle of male Nu/Nu… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Ridge preservation using demineralized bone matrix gel with recombinant human bone morphogenetic protein-2 after tooth extraction: a randomized controlled clinical trial.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons • 2014
View 1 Excerpt

Similar Papers

Loading similar papers…