Addition of dextrose 3.5% to intrathecal sufentanil for labour analgesia reduces pruritus

@article{Abouleish2000AdditionOD,
  title={Addition of dextrose 3.5\% to intrathecal sufentanil for labour analgesia reduces pruritus},
  author={A. Abouleish and D. Portnoy and E. Abouleish},
  journal={Canadian Journal of Anesthesia},
  year={2000},
  volume={47},
  pages={1171-1175}
}
Purpose: To determine whether the addition of a low concentration (3.5%) of dextrose would minimize pruritus while maintaining the quality of analgesia.Methods: In a double blind study 48 parturients in early labour were randomized to one of two study groups: dextrose (Dex, n=24; 10 μg sufentanil in dextrose 3.5%), or normal saline (NS, n=24; 10 μg sufentanil in normal saline). Parturients received the study drug as the intrathecal injection of the combined spinal-epidural (CSE) technique for… Expand
Impact of Baricity of Bupivacaine on Intrathecal Fentanyl-Associated Pruritus during Combined Spinal/Epidural Anesthesia for Labor
TLDR
Hyperbaric bupivacaine reduces both the incidence and severity of pruritus associated with intrathecal fentanyl in laboring parturients when compared to the isobaric formulation. Expand
Effects of intrathecal bupivacaine and bupivacaine plus sufentanil in elderly patients undergoing transurethral resection.
TLDR
Due to the fact that less motor block was observed and the time to first analgesic request was longer, the combination of bupivacaine + sufentanil might be appropriate for patients undergoing TUR. Expand
Intrathecal Opioids for Combined Spinal-Epidural Analgesia during Labour
TLDR
Comparisons of the CSE technique with standard epidural practices have shown that both are effective means of providing analgesia during labour, and the decision to choose a C SE technique depends on the experience of the anaesthesia provider and the local availability of drugs, equipment and monitoring capabilities. Expand
Combined Spinal-Epidural (CSE) for Labor and Delivery
TLDR
The goal of neuraxial labor analgesia is to provide laboring women with safe relief of their pain without affecting their awareness, motor function, progress of labor, or fetal well-being. Expand
Drugs in anaesthesia
TLDR
Isoflurane depresses electroencephalographic and medial thalamic responses to noxious stimulation via an indirect spinal action and alters the recirculatory pharmacokinetics of physiologic markers. Expand
Compliance with the CONSORT checklist in obstetric anaesthesia randomised controlled trials.
TLDR
The purpose of this study was to determine how closely randomised controlled trials in obstetric anaesthesia adhere to the CONSORT checklist. Expand
Opioid Receptor Agonists and Antagonists
Sufentanil intratecal associado ou não a bupivacaína para analgesia de parto

References

SHOWING 1-10 OF 10 REFERENCES
The Addition of Bupivacaine to Intrathecal Sufentanil for Labor Analgesia
TLDR
The addition of 2.5 mg of bupivacaine to 10 micro gram of intrathecal sufentanil significantly prolonged labor analgesia without adverse maternal or fetal effects. Expand
Does Dextrose Affect Analgesia or the Side Effects of Intrathecal Sufentanil?
TLDR
The authors conclude that the addition of dextrose to intrathecal sufentanil injected into patients in the sitting position reduces the duration of analgesia without significantly reducing side effects with the exception of pruritus, and therefore does not improve the clinical utility of intratanil. Expand
Intrathecal sufentanil for labor analgesia--sensory changes, side effects, and fetal heart rate changes.
TLDR
This study evaluated intrathecal (IT) sufentanil for labor analgesia with respect to sensory changes, side effects, and fetal heart rate (FHR) changes to find out whether these changes were associated with adverse neonatal outcome or not. Expand
Intrathecal sufentanil labor analgesia: the effects of adding morphine or epinephrine.
TLDR
Because women in the morphine group experienced significantly more side effects throughout the study period, it is recommended that intrathecal morphine is not recommended for labor analgesia. Expand
Baricity, Needle Direction, and Intrathecal Sufentanil Labor Analgesia
TLDR
Little or no labor analgesia developed for patients receiving sufentanil with dextrose, suggesting that a supraspinal action may contribute to intrathecal sufENTanil's analgesic efficacy. Expand
Addition of opioids alters the density and spread of intrathecal local anesthetics? Anin vitro study
TLDR
The addition of fentanyl reduces the density of IB in vitro and alters its movement in simulated CSF inclinical practice, which may prove to be important in predicting the level of spinal block in clinical practice. Expand
Densities of Dextrose-Free Intrathecal Local Anesthetics, Opioids, and Combinations Measured at 37 degrees C
TLDR
Dextrose-free anesthetic medications are commonly used to provide subarachnoid anesthesia and analgesia and attempts to attribute postural effects to the baricity of these drugs requires establishment of accurate density values, which may facilitate elucidation of the mechanisms underlying the behavior of dextrose-based anesthetics. Expand
Combined spinal-epidural analgesia in advanced labour
TLDR
The absence of motor blockade may facilitate maternal expulsive efforts or positioning during the second stage of labour, and the technique allows for profound analgesia with a rapid onset and few bothersome side effects. Expand
Itching after epidural and spinal opiates
TLDR
A hypothesis to explain spinal opiate‐induced itching is stated and the possible mechanisms of the effect are explored and benefit may be derived from better understanding the phenomenon. Expand