Addition of Multimodal Therapy to Standard Management of Steady State Sickle Cell Disease

@inproceedings{Okpala2013AdditionOM,
  title={Addition of Multimodal Therapy to Standard Management of Steady State Sickle Cell Disease},
  author={Iheanyi Okpala and Osita Uchenna Ezenwosu and Anthony Nnaemeka Ikefuna and Augustine Duru and Barth F Chukwu and Anazoeze Jude Madu and Theresa Ukamaka Nwagha and Sunday Ocheni and Obike Goodswill Ibegbulam and Ifeoma Josephine Emodi and Uche Anike and Charles Emeka Nonyelu and Chukwudi Simon Anigbo and Kingsley Agu and Ifeoma Ajuba and Awele Chukwura and Ogechukwu Ugwu and Uche Ololo},
  booktitle={ISRN hematology},
  year={2013}
}
Most people on folic acid to boost erythropoiesis and prophylactic antimicrobials, the standard management of steady state sickle cell disease (SCD), have unacceptable numbers of crises. The objective of this study was to evaluate the effects of adding multimodal therapy with potassium thiocyanate and omega-3 fatty acids to the standard management of steady state SCD. Pre- and post-treatment numbers of crises and other disease indices were compared in 16 HbSS individuals on folic acid and… CONTINUE READING