Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme

@article{Sotelo2006AddingCT,
  title={Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme},
  author={J. Sotelo and Eduardo Briceo and Miguel Lpez-Gonzlez},
  journal={Annals of Internal Medicine},
  year={2006},
  volume={144},
  pages={337-343}
}
  • J. Sotelo, Eduardo Briceo, Miguel Lpez-Gonzlez
  • Published 2006
  • Medicine
  • Annals of Internal Medicine
  • Context The median survival for patients with glioblastoma multiforme is 1 year despite aggressive treatment. Chloroquine interferes with cellular mechanisms that might cause treatment resistance. Content In this single-center, randomized, double-blind, placebo-controlled trial, 30 patients receiving surgery, chemotherapy, and radiotherapy for glioblastoma multiforme were randomly assigned to receive chloroquine or placebo for 12 months. Median survival was 24 months for patients who received… CONTINUE READING

    Paper Mentions

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    ConditionsAstrocytoma, Grade IV, Glioblastoma
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