Addictive drugs and brain stimulation reward.

@article{Wise1996AddictiveDA,
  title={Addictive drugs and brain stimulation reward.},
  author={R A Wise},
  journal={Annual review of neuroscience},
  year={1996},
  volume={19},
  pages={319-40}
}
  • R A Wise
  • Published 1996 in Annual review of neuroscience
Direct electrical or chemical stimulation of specific brain regions can establish response habits similar to those established by natural rewards such as food or sexual contact. Cocaine, mu and delta opiates, nicotine, phencyclidine, and cannabis each have actions that summate with rewarding electrical stimulation of the medial forebrain bundle (MFB). The reward-potentiating effects of amphetamine and opiates are associated with central sites of action where these drugs also have their direct… CONTINUE READING
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