Addiction, Dopamine, and the Molecular Mechanisms of Memory

@article{Berke2000AddictionDA,
  title={Addiction, Dopamine, and the Molecular Mechanisms of Memory},
  author={Joshua D. Berke and Steven E Hyman},
  journal={Neuron},
  year={2000},
  volume={25},
  pages={515-532}
}
The central feature of drug addiction is compulsive drug of a motor activity, such as sniffing or biting (Randrup use—loss of control over apparently voluntary acts of and Munkvad, 1967). If cocaine or amphetamine is used drug seeking and drug taking (Goldstein, 1994). Addicrepeatedly, some acute drug effects may diminish (“toltion is a chronic disorder, since even after treatment erance”), while others are enhanced (“sensitization”). and extended periods of drug abstinence, the risk of Whether… CONTINUE READING
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