Adderall® produces increased striatal dopamine release and a prolonged time course compared to amphetamine isomers
@article{Joyce2006AdderallPI, title={Adderall® produces increased striatal dopamine release and a prolonged time course compared to amphetamine isomers}, author={B. M. Joyce and P. Glaser and G. Gerhardt}, journal={Psychopharmacology}, year={2006}, volume={191}, pages={669-677} }
RationaleAdderall® is currently used for the treatment of Attention-Deficit Hyperactivity Disorder (ADHD) and is composed of a novel mixture of approximately 24% l-amphetamine and 76% d-amphetamine salts. There are, however, no investigations of the pharmacological effects of this combination in vivo.ObjectivesThe technique of high-speed chronoamperometry using Nafion®-coated single carbon-fiber microelectrodes was used to study amphetamine-evoked dopamine (DA) release produced by Adderall®, d… Expand
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