Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain.

Abstract

Aggregation of the high-affinity IgE receptor (FcepsilonRI) on mast cells activates a tyrosine phosphorylation cascade that is required for adhesion and degranulation events leading to the release of histamine and other inflammatory mediators. The full range of intracellular mediators that regulate this process is unknown. Recent studies have identified a… (More)

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@article{Geng2001AdaptorF, title={Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain.}, author={Liyi Geng and Sophia X. Pfister and S K Kraeft and Christopher E. Rudd}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2001}, volume={98 20}, pages={11527-32} }