Adaptive response and the bystander effect induced by radiation in C3H 10T(1/2) cells in culture.

@article{Sawant2001AdaptiveRA,
  title={Adaptive response and the bystander effect induced by radiation in C3H 10T(1/2) cells in culture.},
  author={Satin G Sawant and Gerhard Randers-Pehrson and Noelle F Metting and Eric Joseph Hall},
  journal={Radiation research},
  year={2001},
  volume={156 2},
  pages={177-80}
}
This paper discusses two phenomena of importance at low doses that have an impact on the shape of the dose-response relationship. First, there is the bystander effect, the term used to describe the biological effects observed in cells that are not themselves traversed by a charged particle, but are neighbors of cells that are; this exaggerates the effect of small doses of radiation. Second, there is the adaptive response, whereby exposure to a low level of DNA stress renders cells resistant to… CONTINUE READING

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  • S. G. Sawant, G. Randers-Pehrson, C. R. Geard, D. J. Brenner, E. J. Hall, The bystander effect in radiation oncogenesis
  • Transformation in C3H 10T1⁄2 cells in vitro can…
  • 2001
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Single - particle irradiation of mammalian cells at the Radiological Research Accelerator Facility : Induction of chromosomal changes

  • D. J. Brenner, G. Randers-Pehrson, S. A. Marino
  • Radiat . Res .
  • 2001

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