Adaptive response: stimulated DNA repair or decreased damage fixation?

@article{Szumiel2005AdaptiveRS,
  title={Adaptive response: stimulated DNA repair or decreased damage fixation?},
  author={Irena Szumiel},
  journal={International journal of radiation biology},
  year={2005},
  volume={81 3},
  pages={233-41}
}
  • Irena Szumiel
  • Published 2005 in International journal of radiation biology
The aim was to review the present state of knowledge on the adaptive response and attempt to redefine the acknowledged model in the framework of the transcription-based model of damage fixation of Radford (2002). Data are reviewed that suggest that the priming stimulus is the source of signalling that eventually leads to expression of the adaptive response. For a certain time, the 'primed' cell can then respond to the challenge dose by an increased recovery, as compared with the control one. An… CONTINUE READING

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