Adaptive regulation of brush-border amino acid transport in a chronic excluded jejunal limb.

@article{Salloum1991AdaptiveRO,
  title={Adaptive regulation of brush-border amino acid transport in a chronic excluded jejunal limb.},
  author={R M Salloum and Bruce R. Stevens and Wiley W. Souba},
  journal={The American journal of physiology},
  year={1991},
  volume={261 1 Pt 1},
  pages={G22-7}
}
We examined the alterations in brush-border glutamine transport that occurred in a surgically defunctionalized jejunal limb excluded from mucosal food contact. Dogs were surgically prepared with Roux-en-Y gastrojejunostomies to permit same-intestine comparisons of glutamine transport and glutaminase activity in jejunal segments that were in incontinuity or excluded for a 6-mo period. Transport of glutamine, alanine, and glucose was measured in brush-border membrane vesicles prepared from each… CONTINUE READING