• Corpus ID: 221507535

Adaptive preferential sampling in phylodynamics.

@article{Cappello2020AdaptivePS,
  title={Adaptive preferential sampling in phylodynamics.},
  author={Lorenzo Cappello and Julia A. Palacios},
  journal={ArXiv},
  year={2020}
}
Longitudinal molecular data of rapidly evolving viruses and pathogens provide information about disease spread and complement traditional surveillance approaches based on case count data. The coalescent is used to model the genealogy that represents the sample ancestral relationships. The basic assumption is that coalescent events occur at a rate inversely proportional to the effective population size $N_{e}(t)$, a time-varying measure of genetic diversity. When the sampling process (collection… 

Statistical Challenges in Tracking the Evolution of SARS-CoV-2.

TLDR
The models and methods currently used to monitor the spread of SARS-CoV-2 are described, long-standing and new statistical challenges are discussed, and a method for tracking the rise of novel variants during the epidemic is proposed.

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