Adaptive microbial response to low-level benzalkonium chloride exposure.

@article{Kampf2018AdaptiveMR,
  title={Adaptive microbial response to low-level benzalkonium chloride exposure.},
  author={G{\"u}nter Kampf},
  journal={The Journal of hospital infection},
  year={2018},
  volume={100 3},
  pages={
          e1-e22
        }
}
  • G. Kampf
  • Published 1 November 2018
  • Biology, Medicine
  • The Journal of hospital infection

Nonsynonymous mutations in fepR are associated with Listeria adaptation to low concentrations of benzalkonium chloride, but not increased survival in use level concentrations of benzalkonium chloride

Findings from the study show that individual Listeria strains can acquire genetic adaptations that confer resistance to low concentrations of benzalkonium chloride, but these genetic adaptations don’t increase Listersia survival when exposed to concentrations of Benzalkonia chloride used for food contact surface sanitation.

Persistence against benzalkonium chloride promotes rapid evolution of tolerance during periodic disinfection

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N-chlorosuccinimide enhancing the antimicrobial effect of benzalkonium chloride on biofilm Pseudomonas aeruginosa and its interaction mechanisms

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Efflux Pump-Driven Antibiotic and Biocide Cross-Resistance in Pseudomonas aeruginosa Isolated from Different Ecological Niches: A Case Study in the Development of Multidrug Resistance in Environmental Hotspots

This is the first comparison of antibiotic-biocide cross-resistance in samples isolated from different ecological niches and serves as a confirmation of laboratory-based studies on biocide adapted isolates.

Preliminary Study on Disinfectant Susceptibility/Resistance Profiles of Bacteria Isolated from Slaughtered Village Free-Range Chickens in Nairobi, Kenya

This study has demonstrated resistance of the bacterial isolates to various disinfectants at recommended user concentrations, although some of them were susceptible at higher concentration(s) and lower concentrations.

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