Adaptive immunity affects learning behavior in mice.

  title={Adaptive immunity affects learning behavior in mice.},
  author={Anna M Brynskikh and Ted Warren and Julia X Zhu and Jonathan Kipnis},
  journal={Brain, behavior, and immunity},
  volume={22 6},
Regulation of neuronal plasticity by the immune system is an evolving field of modern neuroscience. Here we employ immune deficient mice to examine the role of the immune system in learning behavior of mice in a variety of cognitive tasks. While no motivation or motor function deficits are evident in severe combined immune deficient (scid) mice, there was significant impairment in acquisition of cognitive tasks as compared to wild-type (WT) control mice. Moreover, acute depletion of adaptive… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 78 extracted citations


Publications referenced by this paper.
Showing 1-10 of 39 references

Similar Papers

Loading similar papers…