Adaptive evolution of the Homo mitochondrial genome

  title={Adaptive evolution of the Homo mitochondrial genome},
  author={Boris A. Malyarchuk},
  journal={Molecular Biology},
Adaptive evolution of 12 protein-coding mitochondrial genes in members of genus Homo (Denisova hominin (H. sp. Altai), Neanderthals (H. neanderthalensis) and modern humans (H. sapiens)) has been evaluated by assessing the pattern of changes in the physicochemical properties of amino acid replacements during primate evolution. It has been found that molecular adaptation (positive destabilizing selection) in Homo becomes apparent in the form of 12 radical amino acid replacements accompanied with… 


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