Adaptive evolution after gene duplication in alpha-KT x 14 subfamily from Buthus martensii Karsch.

@article{Cao2005AdaptiveEA,
  title={Adaptive evolution after gene duplication in alpha-KT x 14 subfamily from Buthus martensii Karsch.},
  author={Zhijian Cao and Xin Mao and Xiuling Xu and Jiqun Sheng and Chao Dai and Yingliang Wu and Feng Yu Luo and Yonggang Sha and Dahe Jiang and Wenxin Li},
  journal={IUBMB life},
  year={2005},
  volume={57 7},
  pages={513-21}
}
A series of isoforms of alpha-KT x 14 (short chain potassium channel scorpion toxins) were isolated from the venom of Buthus martensii Karsch by RACE and screening cDNA library methods. These isoforms adding BmKK1--3 and BmSKTx1--2 together shared high homology (more than 97%) with each other. The result of genomic sequence analysis showed that a length 79 bp intron is inserted Ala codes between the first and the second base at the 17th amino acid of signal peptide. The introns of these… CONTINUE READING