Adaptive eradication of methionine and cysteine from cyanobacterial light-harvesting proteins

@article{Mazel1989AdaptiveEO,
  title={Adaptive eradication of methionine and cysteine from cyanobacterial light-harvesting proteins},
  author={Didier Mazel and P. Marliere},
  journal={Nature},
  year={1989},
  volume={341},
  pages={245-248}
}
SULPHUR is unique among the main elements of living cells in that it is covalently bound to biopolymers but does not occur in the biopolymer backbone. Indeed, most of the bacterial sulphur content resides in the methionine and cysteine side-chains of proteins1. The growth yield of an organism under conditions of sulphur limitation could therefore be greatly enhanced by mutations that substitute Met and Cys in the organism's proteins for sulphur-free amino acids. Because the saving in sulphur… CONTINUE READING