Adaptive changes in the motor cortex during and after longterm forelimb immobilization in adult rats.

@article{Viaro2014AdaptiveCI,
  title={Adaptive changes in the motor cortex during and after longterm forelimb immobilization in adult rats.},
  author={Riccardo Viaro and Mirco Budri and Pierantonio Parmiani and Gianfranco Franchi},
  journal={The Journal of physiology},
  year={2014},
  volume={592 10},
  pages={2137-52}
}
Experimental and clinical studies have attempted to evaluate the changes in cortical activity seen after immobilization-induced longterm sensorimotor restriction, although results remain controversial. We used intracortical microstimulation (ICMS), which provides topographic movement representations of the motor areas in both hemispheres with optimal spatial characterization, combined with behavioural testing to unravel the effects of limb immobilization on movement representations in the rat… CONTINUE READING
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