Adaptive and aberrant reward prediction signals in the human brain

  • Jonathan P. Roisera, Klaas E. Stephanb, Eileen M. Joyceb
  • Published 2010

Abstract

Theories of the positive symptoms of schizophrenia hypothesize a role for aberrant reinforcement signaling driven by dysregulated dopamine transmission. Recently, we provided evidence of aberrant reward learning in symptomatic, but not asymptomatic patients with schizophrenia, using a novel paradigm, the Salience Attribution Test (SAT). The SAT is a… (More)

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