Adaptive aberration correction in a confocal microscope.

@article{Booth2002AdaptiveAC,
  title={Adaptive aberration correction in a confocal microscope.},
  author={Martin Booth and M. A. A. Neil and Rimas Ju{\vs}kaitis and Tony Wilson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 9},
  pages={5788-92}
}
The main advantage of confocal microscopes over their conventional counterparts is their ability to optically "section" thick specimens; the thin image slices thus obtained can be used to reconstruct three-dimensional images, a capability which is particularly useful in biological applications. However, it is well known that the resolution and optical sectioning ability can be severely degraded by system or specimen-induced aberrations. The use of high aperture lenses further exacerbates the… CONTINUE READING
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