Adaptive Mutation in Saccharomyces cerevisiae

@article{Heidenreich2007AdaptiveMI,
  title={Adaptive Mutation in Saccharomyces cerevisiae},
  author={Erich Heidenreich},
  journal={Critical Reviews in Biochemistry and Molecular Biology},
  year={2007},
  volume={42},
  pages={285 - 311}
}
  • E. Heidenreich
  • Published 1 January 2007
  • Biology, Medicine
  • Critical Reviews in Biochemistry and Molecular Biology
ABSTRACT Adaptive mutation is a generic term for processes that allow individual cells of nonproliferating cell populations to acquire advantageous mutations and thereby to overcome the strong selective pressure of proliferation-limiting environmental conditions. Prerequisites for an occurrence of adaptive mutation are that the selective conditions are nonlethal and that a restart of proliferation may be accomplished by some genetic change in principle. The importance of adaptive mutation is… 
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