Adaptive Cytoprotection Against Deoxycholate-Induced Injury in Human Gastric Cells In Vitro: Is There a Role for Endogenous Prostaglandins?

@article{Kokoska1998AdaptiveCA,
  title={Adaptive Cytoprotection Against Deoxycholate-Induced Injury in Human Gastric Cells In Vitro: Is There a Role for Endogenous Prostaglandins?},
  author={Evan R. Kokoska and Gregory Smith and Chris L. Rieckenberg and Yashwant G Deshpande and Ali Banan and Thomas A. Miller},
  journal={Digestive Diseases and Sciences},
  year={1998},
  volume={43},
  pages={806-815}
}
The majority of previous work investigatingadaptive cytoprotection has involved in vivo studies,which have suggested that this protective response is inlarge part mediated by endogenous prostaglandins (PGs). The aim of this study was to investigateadaptive cytoprotection under in vitro conditions inhuman gastric cells and to better delineate the role ofendogenous PGs in this protective response. AGS cells (a human gastric carcinoma cell line)were characterized morphologically and subsequently… CONTINUE READING