Adaptive Bolus-Based Set-Point Regulation of Hyperglycemia in Critical Care

Abstract

Critically ill patients are often hyperglycemic and extremely diverse in their dynamics. Consequently, fixed protocols and sliding scales can result in error and poor control. A two-compartment glucose-insulin system model that accounts for time-varying insulin sensitivity and endogenous glucose removal, along with two different saturation kinetics is… (More)

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@article{Lin2004AdaptiveBS, title={Adaptive Bolus-Based Set-Point Regulation of Hyperglycemia in Critical Care}, author={J. Lin and J Geoff Chase and G. M. Shaw and C. V. Doran and C. E. Hann and M. B. Robertson and P. M. Browne and Thomas Lotz and G. C. Wake and Bernard C. Broughton}, journal={The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society}, year={2004}, volume={2}, pages={3463-3466} }