Adapting the Quesant© Nomad™ atomic force microscope for biology and patch-clamp atomic force microscopy

@article{Besch2003AdaptingTQ,
  title={Adapting the Quesant© Nomad™ atomic force microscope for biology and patch-clamp atomic force microscopy},
  author={Steve Besch and Kenneth V. Snyder and P. C. Zhang and Frederick Sachs},
  journal={Cell Biochemistry and Biophysics},
  year={2003},
  volume={39},
  pages={195-210}
}
The Quesant© Nomad™ atomic force microscope (AFM) was modified to produce a reliable patch-clamp AFM for demanding biologic applications. The AFM's laser optics forms the basis of a condenser that allows simultaneous Köhler illumination and AFM imaging on an inverted optical microscope. The original AFM scan head was replaced with plastic and glass to make it biologically inert. A bevel cut in the new scan head permits clearance for patch clamp pipets. Cantilevers are attached to the scan head… CONTINUE READING

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