Adapting human pluripotent stem cells to high-throughput and high-content screening

@article{Desbordes2013AdaptingHP,
  title={Adapting human pluripotent stem cells to high-throughput and high-content screening},
  author={Sabrina C Desbordes and Lorenz P Studer},
  journal={Nature Protocols},
  year={2013},
  volume={8},
  pages={111-130}
}
The increasing use of human pluripotent stem cells (hPSCs) as a source of cells for drug discovery, cytotoxicity assessment and disease modeling requires their adaptation to large-scale culture conditions and screening formats. Here, we describe a simple and robust protocol for the adaptation of human embryonic stem cells (hESCs) to high-throughput… CONTINUE READING