Adaptations of carotid arteries of young and mature rabbits to reduced carotid blood flow.

@article{Langille1989AdaptationsOC,
  title={Adaptations of carotid arteries of young and mature rabbits to reduced carotid blood flow.},
  author={B. Lowell Langille and Michelle Patricia Bendeck and Fred W. Keeley},
  journal={The American journal of physiology},
  year={1989},
  volume={256 4 Pt 2},
  pages={H931-9}
}
Adaptive responses of rabbit common carotid arteries were examined after 70-80% reductions in blood flow produced by ipsilateral external carotid artery ligation. These flow reductions elicited growth inhibition of arterial wall tissue in immature rabbits. Specifically, experimental carotid arteries exhibited DNA levels significantly lower, by 35%, than contralateral control arteries 1 mo after external carotid ligation. Lower elastin contents (38%) were also observed, although collagen… CONTINUE READING

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