Adaptations in the muscle cell to training: role of the Na+-K+-Atpase.

  title={Adaptations in the muscle cell to training: role of the Na+-K+-Atpase.},
  author={Henry James Green},
  journal={Canadian journal of applied physiology = Revue canadienne de physiologie appliquee},
  volume={25 3},
The plasticity of skeletal muscle is evident following the onset of regular contractile activity where extensive adaptations can be observed at all levels of organization. Among the properties subject to altered regulation is the Na+-K+-ATPase, an integral membrane protein distributed throughout the sarcolemma and t-tubule, which functions to maintain high Na+ and K+ transmembrane gradients. This protein is uniquely positioned to control muscle excitation and contraction processes, metabolic… CONTINUE READING