Adaptation to stress in yeast: to translate or not?

  title={Adaptation to stress in yeast: to translate or not?},
  author={Clare E. Simpson and Mark P. Ashe},
  journal={Biochemical Society transactions},
  volume={40 4},
For most eukaryotic organisms, including Saccharomyces cerevisiae, the rapid inhibition of protein synthesis forms part of a response to stress. In order to balance the changing conditions, precise stress-specific alterations to the cell's proteome are required. Therefore, in the background of a global down-regulation in protein synthesis, specific proteins are induced. Given the level of plasticity required to enable stress-specific alterations of this kind, it is surprising that the… CONTINUE READING

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