Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise.

@article{Burniston2009AdaptationOT,
  title={Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise.},
  author={Jatin G Burniston},
  journal={Proteomics},
  year={2009},
  volume={9 1},
  pages={106-15}
}
Endurance training improves cardiac function and protects against heart disease. The rodent intensity-controlled running model replicates endurance exercise in humans and can be used to investigate molecular adaptations in the heart. Rats (n = 6, 280 +/- 3 g) performed exercise tests to measure their peak oxygen uptake (VO2peak) and training was prescribed at 70-75% VO2 peak for 30 min, 4 days/wk. Hearts were isolated 4 h after a final VO2peak test and left ventricle proteomes compared to… CONTINUE READING
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