Adaptation of the distal convoluted tubule of the rat. Structural and functional effects of dietary salt intake and chronic diuretic infusion.

@article{Ellison1989AdaptationOT,
  title={Adaptation of the distal convoluted tubule of the rat. Structural and functional effects of dietary salt intake and chronic diuretic infusion.},
  author={David H Ellison and Heino Vel{\'a}zquez and Fred S. Wright},
  journal={The Journal of clinical investigation},
  year={1989},
  volume={83 1},
  pages={113-26}
}
We studied the effects of dietary NaCl intake on the renal distal tubule by feeding rats high or low NaCl chow or by chronically infusing furosemide. Furosemide-treated animals were offered saline as drinking fluid to replace urinary losses. Effects of naCl intake were evaluated using free-flow micropuncture, in vivo microperfusion, and morphometric techniques. Dietary NaCl restriction did not affect NaCl delivery to the early distal tubule but markedly increased the capacity of the distal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 78 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 26 references

Adaptation of distal tubule to increased fluid delivery

  • J. H. Galla, K. A. Kirchner, T. A. Kotchen, R. G. Luke
  • Kidney Int .
  • 1987

Thia - zide - sensitive sodium chloride cotransport in early distal tubule

  • L. S. Costanzo
  • Am . J . Physiol .
  • 1987

Effect of dietary NaCl on chloride uptake in rat collecting duct segment

  • J. H. Galla, D. N. Bonduris, S. L. Dumbauld, R. G. Luke
  • Am . J . Physio .
  • 1986

Effects ofdiuretic drugs on Na , Cl , and K transport by rat renal distal tubue

  • L. G. Fine, T. Bradley
  • Am . J . Physio .
  • 1986

Sodium reabsorption in the distal tubular system

  • M. B. Burg
  • The Kidney : Physiology and Pathophysiology
  • 1986

Similar Papers

Loading similar papers…