Adaptation of renal sulfate transport in response to dietary sulfate intake in guinea pigs.


Inorganic sulfate reabsorption was studied during sulfate infusion in guinea pigs stabilized on high-sulfate, normal-sulfate or low-sulfate diets. Guinea pigs stabilized on a low-sulfate diet exhibited 86-91% fractional sulfate reabsorption at normal plasma sulfate concentrations. Fractional renal sulfate reabsorption in animals stabilized on a high-sulfate… (More)