Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients

@inproceedings{Caador2018AdaptationOP,
  title={Adaptation of Pseudomonas aeruginosa to the chronic phenotype by mutations in the algTmucABD operon in isolates from Brazilian cystic fibrosis patients},
  author={Nat{\'a}lia Candido Caçador and Carolina Paulino da Costa Capizzani and L{\'i}dia Alice Gomes Monteiro Marin Torres and Renata Galetti and Oana Ciofu and Ana L{\'u}cia da Costa Darini and Niels H{\o}iby},
  booktitle={PloS one},
  year={2018}
}
Chronic lung infection by Pseudomonas aeruginosa is the leading cause of morbidity and mortality in cystic fibrosis (CF) patients. This is associated with the conversion of the non-mucoid to the mucoid phenotype. However, there is little information about the occurrence of alginate-producing P. aeruginosa in CF patients outside Europe and North America. The aim of the present study was to investigate mutations in the algTmucABD operon in mucoid and non-mucoid isolates from Brazilian CF patients… CONTINUE READING
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