Adaptation of Mycobacteria to Growth Conditions: A Theoretical Analysis of Changes in Gene Expression Revealed by Microarrays

Abstract

BACKGROUND Microarray analysis is a powerful technique for investigating changes in gene expression. Currently, results (r-values) are interpreted empirically as either unchanged or up- or down-regulated. We now present a mathematical framework, which relates r-values to the macromolecular properties of population-average cells. The theory is illustrated by… (More)
DOI: 10.1371/journal.pone.0059883

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@inproceedings{Cox2013AdaptationOM, title={Adaptation of Mycobacteria to Growth Conditions: A Theoretical Analysis of Changes in Gene Expression Revealed by Microarrays}, author={Robert Ashley Cox and Maria Jesus Hervas Garcia}, booktitle={PloS one}, year={2013} }