Adamantane derivatives: Pharmacological and toxicological properties (review)

@article{Spasov2006AdamantaneDP,
  title={Adamantane derivatives: Pharmacological and toxicological properties (review)},
  author={Alexander A. Spasov and T. V. Khamidova and Lyudmila Bugaeva and I. S. Morozov},
  journal={Pharmaceutical Chemistry Journal},
  year={2006},
  volume={34},
  pages={1-7}
}
Original papers describing the biological properties of adamantane-containing drugs reported on the antiviral activity of 1-aminoadamantane [1]. Presently, the amino derivatives of adamantane are widely used for the prophylaxis and treatment of various viral diseases [2 -4 ] and parkinsonism [5 7]. Six adamantane derivatives are currently used in modem medicine, and two novel preparations have been recently certified. 
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TLDR
Behavioral and convulsions studies of the above mentioned amines did not show any dopaminomimetic activity and argue in favor of the existence of a glutamatergic component in the action of these derivatives.
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TLDR
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TLDR
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