Adalimumab for steroid sparing in patients with giant-cell arteritis: results of a multicentre randomised controlled trial.

@article{Seror2014AdalimumabFS,
  title={Adalimumab for steroid sparing in patients with giant-cell arteritis: results of a multicentre randomised controlled trial.},
  author={Rapha{\'e}le Seror and Gabriel Baron and {\'E}ric Hachulla and Michel Debandt and Claire Larroche and Xavier Pu{\'e}chal and François Maurier and Beno{\^i}t de Wazi{\`e}res and Thomas Qu{\'e}m{\'e}neur and Philippe Ravaud and Xavier Mariette},
  journal={Annals of the rheumatic diseases},
  year={2014},
  volume={73 12},
  pages={
          2074-81
        }
}
OBJECTIVES To evaluate the effect of adding a 10-week treatment of adalimumab to a standardised treatment with corticosteroids on the ability to taper more rapidly corticosteroid doses in patients with newly diagnosed giant cell arteritis (GCA). METHODS Patients included in this double-blind, multicentre controlled trial were randomly assigned to receive a 10-week subcutaneous treatment of adalimumab 40 mg every other week or placebo in addition to a standard prednisone regimen (starting dose… CONTINUE READING
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