Adalimumab for Corticosteroid and Infliximab-Resistant Immune Reconstitution Inflammatory Syndrome in the Setting of TB/HIV Coinfection

@inproceedings{Lwin2018AdalimumabFC,
  title={Adalimumab for Corticosteroid and Infliximab-Resistant Immune Reconstitution Inflammatory Syndrome in the Setting of TB/HIV Coinfection},
  author={Nilar Lwin and Michael H. Boyle and Joshua S Davis},
  booktitle={Open forum infectious diseases},
  year={2018}
}
Corticosteroids are the mainstay of therapy for immune reconstitution inflammatory syndrome (IRIS). However, little is known about how to treat IRIS unresponsive to steroids. We report a patient with HIV-TB coinfection who was unresponsive to first prednisolone and then infliximab but whose IRIS resolved with adalimumab. 
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References

Publications referenced by this paper.
SHOWING 1-10 OF 14 REFERENCES

A Paradoxical Treatment for a Paradoxical Condition: Infliximab Use in Three Cases of Mycobacterial IRIS.

  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2016

Adalimumab treatment may replace or enhance the activity of steroids in steroid-refractory tuberculous meningitis

  • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
  • 2012
VIEW 2 EXCERPTS

Treatment of HIV-related inflammatory cerebral cryptococcoma with adalimumab.

  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2010
VIEW 1 EXCERPT

Adalimumab treatment of life-threatening tuberculosis.

  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2009
VIEW 1 EXCERPT