Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily.

@article{Honda1993Ad4BPRS,
  title={Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily.},
  author={Shigenori Honda and Kengo Morohashi and Masayasu Nomura and Hiroyuki Takeya and Masaki Kitajima and Tsuneo Omura},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 10},
  pages={7494-502}
}
Bovine cytochrome P-450(11 beta) gene (CYP11B) has six different cis-acting elements, Ad1, Ad2, Ad3, Ad4, Ad5, and Ad6, in the promoter region. The Ad4 site also exists in the promoter regions of other steroidogenic P-450 genes as well as in CYP11B1. An Ad4-binding protein (Ad4BP) which specifically binds to the Ad4 site was purified from bovine adrenal cortex nuclear extract, and its molecular mass was 53 kDa. A complementary DNA encoding Ad4BP was isolated from a bovine adrenal cortex cDNA… CONTINUE READING

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