Acylic sugar derivatives for GC/MS analysis of 13C-enrichment during carbohydrate metabolism.

@article{Price2004AcylicSD,
  title={Acylic sugar derivatives for GC/MS analysis of 13C-enrichment during carbohydrate metabolism.},
  author={Neil P J Price},
  journal={Analytical chemistry},
  year={2004},
  volume={76 22},
  pages={6566-74}
}
Metabolic profiling with stable-isotope tracers in combination with gas chromatography/mass spectrometry (GC/MS) is a well-established technique for measuring substrate redistribution within metabolic pathways. This analysis relies on the ability to localize and quantify the fractional incorporation of 13C isotope into each carbon atom of precursor-derived metabolites. In this paper, several carbohydrate derivatization procedures (peracetylation, deuterioalditol acetates, and aldononitrile… CONTINUE READING

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