Acylation Stimulating Protein ( ASP ) Deficiency and Altered Adipose Tissue in Alternative Complement Pathway Knockout Mice

Acylation stimulating protein (C3adesArg/ASP) is an adipokine that acts on its receptor C5L2 to stimulate triglyceride (TG) synthesis in adipose tissue. The present study investigated ASP levels in mouse models of obesity and leanness and the effect of ASP deficiency in C3 knockout (C3KO) mice on adipose tissue morphology. Plasma ASP levels in wildtype (WT… (More)