Acylated cholesteryl galactoside as a novel immunogenic motif in Borrelia burgdorferi sensu stricto.

@article{Schrder2003AcylatedCG,
  title={Acylated cholesteryl galactoside as a novel immunogenic motif in Borrelia burgdorferi sensu stricto.},
  author={Nicolas W. J. Schr{\"o}der and Ursula Schombel and Holger Heine and Ulf Berthold G{\"o}bel and Ulrich Zaehringer and R. Randall Schumann},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 36},
  pages={33645-53}
}
Borrelia burgdorferi sensu lato is the causing agent of Lyme disease, an infectious disease frequently occurring in the United States, Europe, and Northern Asia. Currently, diagnosis of and vaccination strategies against this pathogen are exclusively based on proteinaceous structures. Here we report on a novel class of immunogenic glycolipids purified from B. burgdorferi sensu stricto B31. Employing a butanol/water extraction procedure with subsequent Bligh/Dyer extraction of the organic phase… CONTINUE READING