Acyl-coenzyme A:cholesterol acyltransferase-2 (ACAT-2) is responsible for elevated intestinal ACAT activity in diabetic rats.

@article{Hori2004AcylcoenzymeAA,
  title={Acyl-coenzyme A:cholesterol acyltransferase-2 (ACAT-2) is responsible for elevated intestinal ACAT activity in diabetic rats.},
  author={Masaharu Hori and Maki Satoh and Kohichiro Furukawa and Yu-ichiro Sakamoto and Hideki Hakamata and Yoshihiro Komohara and Motohiro Takeya and Yutaka Sasaki and Akira Miyazaki and Seikoh Horiuchi},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2004},
  volume={24 9},
  pages={1689-95}
}
OBJECTIVE Diabetes-induced dyslipidemia is seen in streptozotocin-induced diabetic rats. This is caused, in part, by elevated intestinal acyl-coenzyme A:cholesterol acyltransferase (ACAT) activity. Because two ACAT isozymes (ACAT-1 and ACAT-2) were identified, in the present study we determined which ACAT isozyme was involved in the elevated intestinal ACAT… CONTINUE READING