Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA

@article{Frgeman2005AcylCoABP,
  title={Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA},
  author={Nils J F{\ae}rgeman and Majken C T Wadum and S\oren Feddersen and Mark Burton and Birthe B Kragelund and Jens Knudsen},
  journal={Molecular and Cellular Biochemistry},
  year={2005},
  volume={299},
  pages={55-65}
}
Besides serving as essential substrates for β-oxidation and synthesis of triacylglycerols and more complex lipids like sphingolipids and sterol esters, long-chain fatty acyl-CoA esters are increasingly being recognized as important regulators of enzyme activities and gene transcription. Acyl-CoA binding protein, ACBP, has been proposed to play a pivotal role in the intracellular trafficking and utilization of long-chain fatty acyl-CoA esters. Depletion of acyl-CoA binding protein in yeast… CONTINUE READING