Acyl-CoA binding proteins: Multiplicity and function

  title={Acyl-CoA binding proteins: Multiplicity and function},
  author={Ruanna E. Gossett and Andrey A. Frolov and John B. Roths and William D. Behnke and Ann B. Kier and Friedhelm Schroeder},
The physiological role of long-chain fatty acyl-CoA is thought to be primarily in intermediary metabolism of fatty acids. However, recent data show that nM to μM levels of these lipophilic molecules are potent regulators of cell functionsin vitro. Although long-chain fatty acyl-CoA are present at several hundred μM concentration in the cell, very little long-chain fatty acyl-CoA actually exists as free or unbound molecules, but rather is bound with high affinity to membrane lipids and/or… CONTINUE READING