Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trials

@article{Klassen2002AcyclovirFT,
  title={Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trials},
  author={Terry P Klassen and Elaine Belseck and Natasha Wiebe and Lisa Hartling},
  journal={BMC Pediatrics},
  year={2002},
  volume={2},
  pages={9 - 9}
}
BackgroundAcyclovir has the potential to shorten the course of chickenpox which may result in reduced costs and morbidity. We conducted a systematic review of randomised controlled trials that evaluated acyclovir for the treatment of chickenpox in otherwise healthy children.MethodsMEDLINE, EMBASE, and the Cochrane Library were searched. The reference lists of relevant articles were examined and primary authors and Glaxo Wellcome were contacted to identify additional trials. Two reviewers… 
Acyclovir for treating varicella in otherwise healthy children and adolescents.
TLDR
Acyclovir appears to be effective in reducing the number of days with fever and the maximum number of lesions among otherwise healthy children with chickenpox.
AN EXPERIENCE OF ORAL ACYCLOVIR IN TREATING CHILDREN WITH VARICELLA INFECTION
TLDR
Use of oral acyclovir in varicella infection (chicken pox) seems to limit new rash formation and total duration of illness to an average of five days.
Outcome of chicken pox in adult immunocompetent patients
TLDR
Chicken pox in adult patients in this population presents as a mild infection in majority of the patients, and the rate of complications is low as compared to western population.
A Rare Case of Acyclovir-Induced Thrombocytopenia
TLDR
A case report of a 58-year-old man with acquired immune deficiency syndrome on highly active antiretroviral therapy who went into severe thrombocytopenia on starting acyclovir is presented.
Treatment in the pediatric emergency department is evidence based: a retrospective analysis
TLDR
A retrospective chart review of patients seen in the PED between January 1 and December 31, 2002 demonstrates that a substantial proportion of PED treatment decisions are evidence-based, with most based on studies in pediatric patients.
Acyclovir‐Induced Immune Thrombocytopenia in a Patient with Herpes Zoster of the Trigeminal Nerve
TLDR
This is the first well‐documented report of isolated severe immune thrombocytopenia induced by acyclovir, and Clinicians should be aware of this rare potential adverse reaction, as prompt diagnosis is the cornerstone of appropriate management.
Management of Varicella Gangrenosa: A Life-Threatening Condition from Chickenpox
TLDR
A case of a previously healthy 12-month-old boy presenting with sepsis due to Varicella gangrenosa is described and the significance of acyclovir in the management of chickenpox complicated by moist gangrene due to bacterial superinfection is emphasized.
Varicella-Related Hospitalization and Emergency Department Visit Rates, Before and After Introduction of Varicella Vaccine, Among White and Black Children in Hamilton County, Ohio
TLDR
Varicella-related hospitalization and ED visit rates decreased significantly for both white and black children in Hamilton County, Ohio, after the introduction of varicella vaccine, and the racial disparity found before licensure decreased after licensure.
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TLDR
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TLDR
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TLDR
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TLDR
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